Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GrimAge: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| Alzheimer's disease | biomarker_for | disease | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| GrimAge Acceleration as a Cell-Type-Resolved CSF Biomarker P | 0.369 | - | Epigenetic clocks as biomarkers for Alzh |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-25 | 6 hypotheses Top: 0.387
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Association of CSF α-synuclein seed amplification assay positivity with disease [PMID:39428831] | Tosun, Hausle, Thropp, Concha-Marambio, | Alzheimer's & dementia : the j | 2025 | 0 |
| CSF markers of vascular injury correlate with tau and cognitive decline in early [PMID:41319164] | Miners, Roy, Love | Alzheimer's & dementia : the j | 2025 | 0 |
| Association of CSF α-synuclein seed amplification assay positivity with disease [PMID:39428831] | Unknown | Alzheimer's & dementia : the j | 2025 | 0 |
| CSF markers of vascular injury correlate with tau and cognitive decline in early [PMID:41319164] | Unknown | Alzheimer's & dementia : the j | 2025 | 0 |
| Sex Differences in Alzheimer's Disease. [PMID:37030962] | Aggarwal, Mielke | Neurologic clinics | 2023 | 0 |
| Sex Differences in Alzheimer's Disease. [PMID:37030962] | Unknown | Neurologic clinics | 2023 | 0 |
| DunedinPACE, a DNA methylation biomarker of the pace of aging. [PMID:35029144] | Belsky DW, Caspi A, Corcoran DL | Elife | 2022 | 0 |
| Epigenetic GrimAge acceleration and cognitive impairment in bipolar disorder. [PMID:35810614] | Lima CNC, Suchting R, Scaini G | Eur Neuropsychopharmacol | 2022 | 0 |
| Epigenetic clock: A promising biomarker and practical tool in aging. [PMID:36206857] | Duan R, Fu Q, Sun Y | Ageing Res Rev | 2022 | 0 |
| DNA methylation GrimAge version 2. [PMID:36516495] | Lu AT, Binder AM, Zhang J | Aging (Albany NY) | 2022 | 0 |
| CSF tau microtubule binding region identifies tau tangle and clinical stages of [PMID:33283854] | Horie K, Barthélemy NR, Sato C, Bateman | Brain : a journal of neurology | 2021 | 0 |
| CSF tau microtubule binding region identifies tau tangle and clinical stages of [PMID:33283854] | Horie K, Barthélemy NR, Sato C, Bateman | Brain : a journal of neurology | 2021 | 0 |
| Impaired glymphatic function and clearance of tau in an Alzheimer's disease mode [PMID:32705145] | Harrison IF, Ismail O, Machhada A, Colga | Brain : a journal of neurology | 2020 | 0 |
| Impaired glymphatic function and clearance of tau in an Alzheimer's disease mode [PMID:32705145] | Harrison IF, Ismail O, Machhada A, Colga | Brain : a journal of neurology | 2020 | 0 |
| DNA methylation GrimAge strongly predicts lifespan and healthspan. [PMID:30669119] | Lu AT, Quach A, Wilson JG | Aging (Albany NY) | 2019 | 0 |
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning GrimAge in their description or question text
No additional research found