gene

GPR98

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about GPR98: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for GPR98 Gene

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🧬 Gene Info

Gene Symbol	GPR98
Full Name	G Protein-Coupled Receptor 98 (VLGR1)
Chromosome	5q14.3
Function	GPR98 (also known as VLGR1 - Very Large G-Protein Coupled Receptor 1) encodes one of the largest known G-protein coupled receptors, with over 6000 amino acids.
Primary Expression	various brain regions including: - Cerebellum - Purkinje cells and granule cells - Hippocampus - CA1-CA3 regions
Amino Acids	6000 aa
UniProt ID	Q8WXF3
NCBI Gene ID	84059
Ensembl ID	ENSG00000138297
OMIM	602851
GeneCards	GPR98
Human Protein Atlas	GPR98
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: GPR98 — AlphaFold Q8WXF3 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

GPR98 Gene

gene · 1698 words

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ADGRV1 Protein (GPR98)

protein · 594 words

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Pathway Diagram

graph TD
    GPR98["GPR98"]
    neurodegeneration["neurodegeneration"]
    GPR98 -->|"implicated_in"| neurodegeneration
    style GPR98 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning GPR98 in their description or question text

No additional research found