Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GNG4PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Gng4 Protein — G Protein Subunit Gamma 4 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
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| Gene Symbol | GNG4PROTEIN |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | the cerebellum: |
| Amino Acids | 70 aa |
| GeneCards | GNG4PROTEIN |
| Human Protein Atlas | GNG4PROTEIN |
| Small polypeptide | ~68-70 amino acids |
| C-terminal CAAX motif | Cys-aliphatic-aliphatic-X, undergoes prenylation |
| Prenylation | Essential for membrane targeting and function |
| Gβ binding interface | Mediates dimer formation with Gβ subunits |
| Purkinje cell function | Gβγ signaling in cerebellar neurons |
| Motor learning | Modulation of synaptic plasticity |
| Coordination | Regulation of motor output pathways |
| Olfactory receptor regulation | Gβγ dimers modulate olfactory signaling |
| Odor adaptation | Gβγ contributes to sensory adaptation |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
GNG4PROTEIN["GNG4PROTEIN"]
neurodegeneration["neurodegeneration"]
GNG4PROTEIN -->|"implicated_in"| neurodegeneration
style GNG4PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
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Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning GNG4PROTEIN in their description or question text
No additional research found