gene

GNB2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GNB2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for GNB2 — G Protein Subunit Beta 2

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🧬 Gene Info

Gene Symbol	GNB2
Full Name	G Protein Subunit Beta 2
Chromosome	7q22.1
Function	Receptor activation: An extracellular ligand activates a GPCR at the plasma membrane
Primary Expression	Brain (cortex, hippocampus, cerebellum), Heart, Liver, Immune cells
Subcellular Localization	</strong></td><td>Cytoplasm, plasma membrane, Golgi apparatus, endosomes</td></tr>
Molecular Weight	37 kDa
Amino Acids	340 aa
Pathways	PI3K, PI3K signaling, MAPK, MAPK signaling
UniProt ID	P62879
NCBI Gene ID	2783
Ensembl ID	ENSG00000186470
OMIM	139311
GeneCards	GNB2
Human Protein Atlas	GNB2
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: GNB2 — AlphaFold P62879 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

GNB2 Protein

protein · 1058 words

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GNB2 — G Protein Subunit Beta 2

gene · 660 words

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Pathway Diagram

graph TD
    GNB2["GNB2"]
    neurodegeneration["neurodegeneration"]
    GNB2 -->|"implicated_in"| neurodegeneration
    style GNB2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning GNB2 in their description or question text

No additional research found