gene

FGF4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FGF4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

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Summary

FGF4 encodes a potent mitogenic factor of the FGF4 subfamily with roles in neural progenitor proliferation, embryonic brain development, synaptic plasticity, and potential implications for neurodegenerative disease and neural regeneration.

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🧬 Gene Info

Gene Symbol	FGF4
Full Name	Fibroblast Growth Factor 4
Chromosome	11q13
Function	encodes a member of the FGF4 subfamily of fibroblast growth factors.
Molecular Weight	22.7 kDa
Amino Acids	206 aa
UniProt ID	P08620
NCBI Gene ID	2249
Ensembl ID	ENSG00000075388
OMIM	164980
GeneCards	FGF4
Human Protein Atlas	FGF4
FGF4	Original member (HST-1)
FGF5	Originally identified as an oncogene
FGF6	Proto-oncogene with overlapping functions
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: FGF4 — AlphaFold P08620 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

FGF4 — Fibroblast Growth Factor 4

gene · 1668 words

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Pathway Diagram

graph TD
    FGF4["FGF4"]
    neurodegeneration["neurodegeneration"]
    FGF4 -->|"implicated_in"| neurodegeneration
    style FGF4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning FGF4 in their description or question text

No additional research found