gene

FGF3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FGF3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Debates

Summary

Fibroblast Growth Factor 3

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🧬 Gene Info

Gene Symbol	FGF3
Full Name	Fibroblast Growth Factor 3
Aliases	INT1, HST, HST-1, INT2, HBGF-3 [@fgf2005]
Chromosome	11q13.3 (GRCh38: 69809968..69819416)
Protein Type	Gene
Function	FGF3 functions as a mitogenic factor that activates FGFR signaling pathways
Primary Expression	regions including the hippocampus, cortex, and cerebellum, where it continues to play roles in
Molecular Weight	~24 kDa
Amino Acids	181 aa
UniProt ID	P11487
NCBI Gene ID	2248
Ensembl ID	ENSG00000186891
GeneCards	FGF3
Human Protein Atlas	FGF3
Official Name	Fibroblast Growth Factor 3
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: FGF3 — AlphaFold P11487 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Fibroblast Growth Factor 3

gene · 695 words

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Pathway Diagram

graph TD
    FGF3["FGF3"]
    neurodegeneration["neurodegeneration"]
    FGF3 -->|"implicated_in"| neurodegeneration
    style FGF3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
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Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning FGF3 in their description or question text

No additional research found