Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FANCG: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | FANCG |
| Chromosome | 9p13.3 |
| Function | encodes a critical component of the Fanconi anemia (FA) DNA repair pathway. |
| Molecular Weight | 68 kDa |
| Amino Acids | 622 aa |
| Exons | 14 |
| Ensembl ID | ENSG00000221838 |
| GeneCards | FANCG |
| Human Protein Atlas | FANCG |
| Human-Mouse | 82% identical at the amino acid level |
| Human-Zebrafish | 65% identical |
| Drosophila | Partial ortholog with 40% identity |
| Yeast | No clear ortholog |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
FANCG["FANCG"]
neurodegeneration["neurodegeneration"]
FANCG -->|"implicated_in"| neurodegeneration
style FANCG fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning FANCG in their description or question text
No additional research found