gene

ELOVL5

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ELOVL5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for ELOVL5 - Fatty Acid Elongase 5

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🧬 Gene Info

Gene Symbol	ELOVL5
Full Name	Elongation of Very Long Chain Fatty Acids 5
Aliases	Page for ELOVL5
Protein Type	Enzyme
Function	ELOVL5 (Elongation of Very Long Chain Fatty Acids 5) is an endoplasmic reticulum membrane-bound enzyme that catalyzes the rate-limiting step in the elongation of polyunsaturated fatty acids (PUFAs).
Primary Expression	multiple tissues with brain-relevant localization: - Brain: Cerebellum (Purkinje cells), hippocampus, [cortex](/brai
UniProt ID	[Q9NYP7](https://www.uniprot.org/uniprot/Q9NYP7)
Ensembl ID	ENSG00000012660
GeneCards	ELOVL5
Human Protein Atlas	ELOVL5
Brain	Cerebellum (Purkinje cells), hippocampus, cortex
Retina	Photoreceptor cells and retinal pigment epithelium
Liver	Major site of fatty acid elongation
Testis	High expression for sperm membrane synthesis
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

ELOVL5 - Fatty Acid Elongase 5

gene · 619 words

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Pathway Diagram

graph TD
    ELOVL5["ELOVL5"]
    neurodegeneration["neurodegeneration"]
    ELOVL5 -->|"implicated_in"| neurodegeneration
    style ELOVL5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning ELOVL5 in their description or question text

No additional research found