EIF4E

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolEIF4E
Nameeukaryotic translation initiation factor 4E
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transf

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