gene

DNC1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DNC1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

8Connections

0Hypotheses

0Analyses

8Outgoing

0Incoming

0Experiments

0Debates

Summary

Gene profile: DNC1 (PARK19)

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🧬 Gene Info

Gene Symbol	DNC1
Full Name	Dynein Cytoplasmic 1
Aliases	PARK19
Chromosome	9q34.11
Function	Under physiological conditions, DNC1 participates in essential cellular processes:
Primary Expression	Brain, Spinal cord, Testis
Amino Acids	105 aa
UniProt ID	Q9H0Y9
NCBI Gene ID	1775
Ensembl ID	ENSG00000175920
OMIM	614037
GeneCards	DNC1
Human Protein Atlas	DNC1
Associated Diseases	motor_neuron_degeneration
Interactions	DNC2, DNC3
KG Connections	8 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: DNC1 — AlphaFold Q9H0Y9 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

DNC1 — Dynein Cytoplasmic 1

gene · 660 words

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Pathway Diagram

graph TD
    DNC1["DNC1"]
    autophagosomes["autophagosomes"]
    DNC1 -->|"regulates"| autophagosomes
    motor_neuron_degeneration["motor_neuron_degeneration"]
    DNC1 -->|"causes"| motor_neuron_degeneration
    DNC3["DNC3"]
    DNC1 -->|"interacts with"| DNC3
    DNC2["DNC2"]
    DNC1 -->|"interacts with"| DNC2
    dynactin_complex["dynactin_complex"]
    DNC1 -->|"component of"| dynactin_complex
    meiotic_chromosome_segregation["meiotic_chromosome_segregation"]
    DNC1 -->|"participates in"| meiotic_chromosome_segregation
    spindle_assembly["spindle_assembly"]
    DNC1 -->|"participates in"| spindle_assembly
    spindle_elongation["spindle_elongation"]
    DNC1 -->|"participates in"| spindle_elongation
    neurodegeneration["neurodegeneration"]
    DNC1 -->|"implicated in"| neurodegeneration
    style DNC1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (8)

Target	Relation	Type	Str
autophagosomes	regulates	entity	0.80
motor_neuron_degeneration	causes	phenotype	0.80
DNC3	interacts_with	gene	0.80
DNC2	interacts_with	gene	0.80
dynactin_complex	component_of	entity	0.80
meiotic_chromosome_segregation	participates_in	biological_process	0.70
spindle_assembly	participates_in	biological_process	0.70
spindle_elongation	participates_in	biological_process	0.70

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning DNC1 in their description or question text

No additional research found