protein

DNAJC19

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DNAJC19: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for DNAJC19 Protein

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🔬 Protein Info

Gene Symbol	DNAJC19
Chromosome	3q26.33.
Protein Type	Gene
Function	DNAJC19 is a mitochondrial DNAJ chaperone that plays critical roles in mitochondrial protein import and quality control.
Primary Expression	tissues with high mitochondrial content:
UniProt ID	Q96EV8
Ensembl ID	ENSG00000176490
GeneCards	DNAJC19
Human Protein Atlas	DNAJC19
Mitochondrial protein import	DNAJC19 assists in the translocation of proteins into mitochondria
Iron-sulfur cluster assembly	Essential for Fe-S cluster biogenesis
Mitochondrial proteostasis	Functions as a co-chaperone for mitochondrial Hsp70
Inner membrane organization	Maintains mitochondrial cristae structure
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: DNAJC19 — AlphaFold Q96EV8 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

DNAJC19 Gene

gene · 641 words

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DNAJC19 Protein

protein · 754 words

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Pathway Diagram

graph TD
    DNAJC19["DNAJC19"]
    neurodegeneration["neurodegeneration"]
    DNAJC19 -->|"implicated_in"| neurodegeneration
    style DNAJC19 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning DNAJC19 in their description or question text

No additional research found