Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DBL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | DBL |
| Chromosome | Xq27.1 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Brain, Spleen, Testis, Lymphoid tissues |
| Molecular Weight | 92 kDa |
| Amino Acids | 785 aa |
| Pathways | Wnt, Wnt signaling |
| UniProt ID | P12931 |
| NCBI Gene ID | 9075 |
| Ensembl ID | ENSG00000123146 |
| GeneCards | DBL |
| Human Protein Atlas | DBL |
| RhoA activation | leads to stress fiber formation and contractility |
| Rac1 activation | promotes lamellipodia and membrane ruffling |
| Cdc42 activation | induces filopodia formation |
| Associated Diseases | B-Cell Lymphoma, Prostate Cancer, X-Linked Mental Retardation |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
DBL["DBL"]
neurodegeneration["neurodegeneration"]
DBL -->|"implicated_in"| neurodegeneration
style DBL fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning DBL in their description or question text
No additional research found