CX3CR1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCX3CR1
NameC-X3-C motif chemokine receptor 1
Typeprotein-coding
Sourcemygene

Summary

Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010].

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