gene

CSF2RB

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CSF2RB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🧬 Gene Info

Gene Symbol	GM
Full Name	CSF Receptor Common Beta Chain
Aliases	CSF2RB
Chromosome	22q12.1
Function	Granulocyte-macrophage colony-stimulating factor receptor common beta chain (CSF2RB) is the shared signaling component of the GM-CSF receptor family.
Subcellular Localization	</th><td>Plasma membrane</td></tr>
GeneCards	GM
Human Protein Atlas	GM
CBC1 Domain (1-120 aa)	Proximal membrane, contains WSXWS motif
CBC3 Domain (241-360 aa)	Distal domain for ligand interaction
Transmembrane Domain (361-383 aa)	Single hydrophobic helix
Cytoplasmic Domain (384-800 aa)	Multiple signaling motifs
Databases	GeneCards UniProt NCBI Gene HPA STRING

🔮 Predicted Structure: CSF2RB — AlphaFold P32927 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GM-CSF Receptor Common Beta Chain

protein · 1526 words

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Pathway Diagram

graph TD
    CSF2RB["CSF2RB"]
    neurodegeneration["neurodegeneration"]
    CSF2RB -->|"implicated_in"| neurodegeneration
    style CSF2RB fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning CSF2RB in their description or question text

No additional research found