CRH

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCRH
Namecorticotropin releasing hormone
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the corticotropin-releasing factor family. The encoded preproprotein is proteolytically processed to generate the mature neuropeptide hormone. In response to stress, this hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus, binds to corticotropin releasing hormone receptors and stimulates the release of adrenocorticotropic hormone from the pituitary gland. Marked reduction in this protein has been observed in association with Alzheimer'

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