Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about COX6B1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | COX6B1 |
| Aliases | Cytochrome C Oxidase Subunit 6B1 |
| Chromosome | 19q13.12 |
| Protein Type | Gene |
| Function | Cytochrome c oxidase subunit 6B1 (COX6B1) is a subunit of mitochondrial complex IV (cytochrome c oxidase). |
| Primary Expression | tissues with high oxidative metabolism and is essential for complex IV assembly and function |
| Molecular Weight | 9 kDa |
| Amino Acids | 86 aa |
| Pathways | oxidative phosphorylation |
| UniProt ID | P12074 |
| GeneCards | COX6B1 |
| Human Protein Atlas | COX6B1 |
| Associated Diseases | neurodegeneration |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
COX6B1["COX6B1"]
oxidative_phosphorylation["oxidative phosphorylation"]
Xanthomonas_oryzae_pv_oryzae["Xanthomonas oryzae pv oryzae"]
neurodegeneration["neurodegeneration"]
COX6B1 -->|"activates"| oxidative_phosphorylation
COX6B1 -->|"inhibits"| Xanthomonas_oryzae_pv_oryzae
COX6B1 -->|"implicated in"| neurodegeneration
style COX6B1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
style oxidative_phosphorylation fill:#1a3a1a,stroke:#81c784,stroke-width:2px,color:#fff
style Xanthomonas_oryzae_pv_oryzae fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff
style neurodegeneration fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff| Target | Relation | Type | Str |
|---|---|---|---|
| oxidative phosphorylation | activates | pathway | 0.90 |
| Xanthomonas oryzae pv oryzae | inhibits | entity | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning COX6B1 in their description or question text
No additional research found