gene

COX14

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about COX14: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Comprehensive gene page for COX14 (Cytochrome C Oxidase Assembly Factor 14), a mitochondrial protein essential for complex IV assembly and neuronal survival

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🧬 Gene Info

Gene Symbol	COX14
Full Name	Cytochrome C Oxidase Assembly Factor 14
Protein Type	Enzyme
Function	COX14 functions as a specialized assembly factor that stabilizes early assembly intermediates and facilitates the incorporation of subunits into the growing complex.
Ensembl ID	ENSG00000178826
GeneCards	COX14
Human Protein Atlas	COX14
Transmembrane domain	Anchors the protein to the inner mitochondrial membrane
Matrix-facing domain	Contains functional regions for assembly factor activity
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

COX14 — Cytochrome C Oxidase Assembly Factor 14

gene · 3101 words

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Pathway Diagram

graph TD
    COX14["COX14"]
    neurodegeneration["neurodegeneration"]
    COX14 -->|"implicated_in"| neurodegeneration
    style COX14 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning COX14 in their description or question text

No additional research found