Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CNTN2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Contactin 2 (TAG-1/axonin-1) in neural development, epilepsy, autism and neurodegenerative diseases
No AI portrait yet
| Gene Symbol | CNTN2 |
| Full Name | Contactin 2 |
| Aliases | TAG-1/axonin-1 |
| Chromosome | 1q32.1. |
| Function | Ig-like domains: Six immunoglobulin-like domains in the extracellular region that mediate homophilic and heterophilic interactions |
| Primary Expression | High in brain (hippocampus, cerebellum, cortex), developing neurons, oligodendrocyte precursors |
| Molecular Weight | 160 kDa |
| Amino Acids | 438 aa |
| UniProt ID | Q9H5Y1 |
| NCBI Gene ID | 6900 |
| Ensembl ID | ENSG00000167644 |
| OMIM | 164395 |
| GeneCards | CNTN2 |
| Human Protein Atlas | CNTN2 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
CNTN2["CNTN2"]
neurodegeneration["neurodegeneration"]
CNTN2 -->|"implicated_in"| neurodegeneration
style CNTN2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CNTN2 in their description or question text
No additional research found