gene

CLN8

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CLN8: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

0Debates

Summary

Page for CLN8 Gene - Ceroid Lipofuscinosis, Neuronal 8

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🧬 Gene Info

Gene Symbol	CLN8
Aliases	Page for CLN8 Gene
Chromosome	8p23.2
Protein Family	CLN8 family, ER membrane proteins
Function	It contains multiple transmembrane domains and cytosolic loops[2].
Subcellular Localization	the ER membrane. It contains multiple transmembrane domains and cytosolic loops<sup>[2]</sup>
Molecular Weight	32 kDa
Amino Acids	286 aa
Exons	4
UniProt ID	Q9UHD2
NCBI Gene ID	2055
Ensembl ID	ENSG00000154164
OMIM	607897
GeneCards	CLN8
Human Protein Atlas	CLN8
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CLN8 — AlphaFold Q9UHD2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

CLN8 Gene - Ceroid Lipofuscinosis, Neuronal 8

gene · 804 words

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CLN8 Protein

protein · 647 words

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Pathway Diagram

graph TD
    CLN8["CLN8"]
    neurodegeneration["neurodegeneration"]
    CLN8 -->|"implicated_in"| neurodegeneration
    style CLN8 fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
    style neurodegeneration fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CLN8 in their description or question text

No additional research found