Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CLDN18: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| Gastric Cancer | biomarker_for | disease | 0.95 |
| Gastric Epithelium | expressed_in | cell_type | 0.95 |
| Malignant Transformation | associated_with | process | 0.90 |
| Tight Junction | involved_in | mechanism | 0.90 |
| Solid Tumors | biomarker_for | disease | 0.75 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Zolbetuximab | targets | drug | 0.98 |
| High-Affinity Monoclonal Antibodies | targets | drug | 0.85 |
| Bispecific Antibodies | targets | drug | 0.85 |
| Chimeric Antigen Receptor T Cells | targets | drug | 0.85 |
| Antibody-Drug Conjugates | targets | drug | 0.85 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CLDN18 in their description or question text
No additional research found