Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CHRM3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
CHRM3 (Cholinergic Receptor Muscarinic 3) - Gq-coupled muscarinic receptor involved in smooth muscle contraction, glandular secretion, memory formation, and neurodegenerative disease pathophysiology
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| Gene Symbol | CHRM3 |
| Aliases | Cholinergic Receptor Muscarinic 3 |
| Chromosome | 1q41 |
| Function | encodes a 532-amino acid protein. |
| Primary Expression | regions involved in cognition and movement, though its functions are less well-characterized than M1 and M4 receptors |
| Amino Acids | 532 aa |
| GeneCards | CHRM3 |
| Human Protein Atlas | CHRM3 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
CHRM3["CHRM3"]
neurodegeneration["neurodegeneration"]
CHRM3 -->|"implicated_in"| neurodegeneration
style CHRM3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CHRM3 in their description or question text
No additional research found