Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CELF3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
CELF3 is an RNA-binding protein involved in post-transcriptional gene regulation, implicated in epilepsy, Alzheimer's Disease, and ALS
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| Gene Symbol | CELF3 |
| Full Name | CUGBP Elav-Like Family Member 3 |
| Chromosome | 11q13.2 |
| Protein Type | RNA-binding protein, splicing factor |
| Function | is a member of the CELF family of RNA-binding proteins that play critical roles in post-transcriptional gene regulation. |
| Primary Expression | the brain, with specific patterns[@nakagawa2020][@tang2023]: |
| Amino Acids | 481 aa |
| UniProt ID | Q8N6W3 |
| NCBI Gene ID | 55568 |
| Ensembl ID | ENSG00000146540 |
| GeneCards | CELF3 |
| Human Protein Atlas | CELF3 |
| Alternative splicing | Regulation of exon inclusion/skipping |
| mRNA stability | Control of transcript degradation |
| Translation | Modulation of protein synthesis |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
CELF3["CELF3"]
neurodegeneration["neurodegeneration"]
CELF3 -->|"implicated_in"| neurodegeneration
style CELF3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CELF3 in their description or question text
No additional research found