gene

CDC42EP2

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about CDC42EP2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for CDC42EP2 Gene (CDC42 Effector Protein 2)

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🧬 Gene Info

Gene Symbol	CDC42EP2
Full Name	CDC42 Effector Protein 2
Chromosome	2q33.3
Function	CDC42 Activation: Active CDC42-GTP binds to CRIB motif
Primary Expression	the brain, particularly in regions associated with learning and memory
Molecular Weight	38 kDa
Amino Acids	340 aa
Exons	10
UniProt ID	[Q8IY95](https://www.uniprot.org/uniprot/Q8IY95)
Ensembl ID	ENSG00000149557
GeneCards	CDC42EP2
Human Protein Atlas	CDC42EP2
N-terminal CRIB domain	Residues 1-90, mediates CDC42 interaction
Central Pro-rich region	Contains multiple SH3-binding sites
C-terminal regulatory domain	Includes phosphorylation sites and protein interaction motifs
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

CDC42EP2 Gene

gene · 1389 words

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Pathway Diagram

graph TD
    CDC42EP2["CDC42EP2"]
    neurodegeneration["neurodegeneration"]
    CDC42EP2 -->|"implicated_in"| neurodegeneration
    style CDC42EP2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning CDC42EP2 in their description or question text

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