CD59

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCD59
NameCD59 molecule (CD59 blood group)
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in th

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