Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CBX7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | CBX7 |
| Full Name | Chromobox 7 |
| Chromosome | 22q13.1 |
| Function | CBX7 encodes a PRC1 component with the following normal functions |
| Molecular Weight | 25 kDa |
| UniProt ID | O95931 |
| NCBI Gene ID | 23492 |
| Ensembl ID | ENSG00000105976 |
| OMIM | 607860 |
| GeneCards | CBX7 |
| Human Protein Atlas | CBX7 |
| Transcriptional repression | Maintains silencing of developmental genes |
| Histone recognition | Binds H3K27me3 through chromodomain |
| Chromatin compaction | Facilitates higher-order chromatin structure |
| Cell fate determination | Maintains stem cell identity |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
CBX7["CBX7"]
neurodegeneration["neurodegeneration"]
CBX7 -->|"implicated_in"| neurodegeneration
style CBX7 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CBX7 in their description or question text
No additional research found