CABIN1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCABIN1
Namecalcineurin binding protein 1
Typeprotein-coding
Sourcemygene

Summary

Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants enc

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