gene

CACNG2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CACNG2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

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Summary

CACNG2 (stargazin) is a TARP gamma-2 subunit that modulates AMPA receptor trafficking and synaptic plasticity, implicated in epilepsy, autism, and Alzheimer's disease.

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🧬 Gene Info

Gene Symbol	CACNG2
Full Name	Calcium Voltage-Gated Channel Gamma Subunit 2 (Stargazin)
Aliases	stargazin, Page for CACNG2 Protein
Chromosome	22q12.1
Protein Type	Receptor
Function	modulates AMPA receptor trafficking and synaptic plasticity
Molecular Weight	41 kDa
Amino Acids	323 aa
UniProt ID	Q9Y698
Ensembl ID	ENSG00000166862
GeneCards	CACNG2
Human Protein Atlas	CACNG2
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: CACNG2 — AlphaFold Q9Y698 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

CACNG2 - Stargazin Calcium Channel Gamma-2

gene · 783 words

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CACNG2 Protein - Stargazin Calcium Channel Gamma-2

protein · 613 words

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Pathway Diagram

graph TD
    CACNG2["CACNG2"]
    neurodegeneration["neurodegeneration"]
    CACNG2 -->|"implicated_in"| neurodegeneration
    style CACNG2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CACNG2 in their description or question text

No additional research found