Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about C9orf72 ALS/FTD: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| MDM2-p53 axis | therapeutic_target_for | pathway | 0.90 |
| Poly(PR) | causes | protein | 0.90 |
| C9orf72 ASO | therapeutic_target_for | drug | 0.90 |
| DNA Repair Pathway | associated_with | pathway | 0.75 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-15 | 1 hypotheses Top: 0.661
neurodegeneration | 2025-12-31 | 23 hypotheses Top: 0.755
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.75 · 2026-04-27
closed · Rounds: 4 · Score: 0.58 · 2026-04-27
closed · Rounds: 4 · Score: 0.77 · 2026-04-26
closed · Rounds: 4 · Score: 0.61 · 2026-04-16
Hypotheses and analyses mentioning C9orf72 ALS/FTD in their description or question text
No additional research found