Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Biomarker Panel: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Alzheimer'S Disease | biomarker_for | disease | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Integrated Biomarker Panel for Therapeutic Window Identifica | 0.784 | neurodegeneration | What are the precise temporal dynamics o |
| Neurovascular Permeability Score (NVPS): Composite Plasma + | 0.600 | - | Blood-brain barrier permeability changes |
| Dynamic Microglial Phenotype Switching Biomarker Panel for N | 0.577 | neurodegeneration | What amyloid threshold level is required |
| GrimAge Acceleration as a Cell-Type-Resolved CSF Biomarker P | 0.369 | - | Epigenetic clocks as biomarkers for Alzh |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| Chi3l1 deletion effects on baseline glial activation in mice | validation | baseline neuroinflammation | 0.900 | 0.00 | Chi3l1 knockout mice | proposed | N/A |
| CHI3L1 variant association with AD progression in human patients | exploratory | Alzheimer's disease | 0.850 | 0.00 | human patients | proposed | N/A |
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis [PMID:40771159] | Padilla CM, Lafyatis R, Gibson KF, Morse | Arthritis Care Res (Hoboken) | 2026 | 0 |
| Obstructive sleep apnea, biomarker profiles, and clinical progression in Parkins [PMID:41499940] | Zhu S, An D, Liu X | Sleep Med | 2026 | 0 |
| SuPAR levels are increased in sera of euthymic patients with bipolar disorder an [PMID:41605346] | Kök Kendirlioğlu B, Çörekli Kaymakçı E, | J Affect Disord | 2026 | 0 |
| Chitinase-like Proteins YKL-40 and YKL-39 in Colorectal Cancer. [PMID:41677627] | Ivanova T, Kazakova M, Dikov D, Dzhambov | Cells | 2026 | 0 |
| Correction: CHI3L1: An Emerging Player in Neuroinflammation and Neurodegeneratio [PMID:41699333] | Mushtaq Umar; Seh Bilal Ahmad; Khanday F | Molecular Neurobiology | 2026 | 0 |
| Association of Alzheimer's disease progression with YKL40 levels in peripheral b [PMID:41725729] | Yang Q, Wang R, Pei J, Fu Q, Zhan Y et a | Front Neurol | 2026 | 0 |
| Constitutive neuronal expression and disease-associated upregulation of chitinas [PMID:41762671] | Gaur N, Angerer C, Gunes ZI, Ancau M, Wa | Brain | 2026 | 0 |
| Plasma CHI3L1 as a marker of cognitive and structural brain changes in radiologi [PMID:41953284] | Schneider R, Brand-Arzamendi K, Lim TR, | BMJ Neurol Open | 2026 | 0 |
| Association of CSF α-synuclein seed amplification assay positivity with disease [PMID:39428831] | Tosun, Hausle, Thropp, Concha-Marambio, | Alzheimer's & dementia : the j | 2025 | 0 |
| CSF markers of vascular injury correlate with tau and cognitive decline in early [PMID:41319164] | Miners, Roy, Love | Alzheimer's & dementia : the j | 2025 | 0 |
| Association of CSF α-synuclein seed amplification assay positivity with disease [PMID:39428831] | Unknown | Alzheimer's & dementia : the j | 2025 | 0 |
| CSF markers of vascular injury correlate with tau and cognitive decline in early [PMID:41319164] | Unknown | Alzheimer's & dementia : the j | 2025 | 0 |
| Sex Differences in Alzheimer's Disease. [PMID:37030962] | Aggarwal, Mielke | Neurologic clinics | 2023 | 0 |
| Sex Differences in Alzheimer's Disease. [PMID:37030962] | Unknown | Neurologic clinics | 2023 | 0 |
| DunedinPACE, a DNA methylation biomarker of the pace of aging. [PMID:35029144] | Belsky DW, Caspi A, Corcoran DL | Elife | 2022 | 0 |
| Epigenetic GrimAge acceleration and cognitive impairment in bipolar disorder. [PMID:35810614] | Lima CNC, Suchting R, Scaini G | Eur Neuropsychopharmacol | 2022 | 0 |
| Epigenetic clock: A promising biomarker and practical tool in aging. [PMID:36206857] | Duan R, Fu Q, Sun Y | Ageing Res Rev | 2022 | 0 |
| DNA methylation GrimAge version 2. [PMID:36516495] | Lu AT, Binder AM, Zhang J | Aging (Albany NY) | 2022 | 0 |
| CSF tau microtubule binding region identifies tau tangle and clinical stages of [PMID:33283854] | Horie K, Barthélemy NR, Sato C, Bateman | Brain : a journal of neurology | 2021 | 0 |
| CSF tau microtubule binding region identifies tau tangle and clinical stages of [PMID:33283854] | Horie K, Barthélemy NR, Sato C, Bateman | Brain : a journal of neurology | 2021 | 0 |
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning Biomarker Panel in their description or question text
No additional research found