entity

Biomarker Panel

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Biomarker Panel: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

4Connections
5Hypotheses
0Analyses
1Outgoing
3Incoming
2Experiments
0Debates

No AI portrait yet

Wiki Pages (16)

Knowledge base pages for this entity

Section 179: Advanced Proteomics and Protein Biomarker Panels for CBS/PSP

therapeutic · 2095 words

Combination Biomarker Panels for Alzheimer's Disease

biomarker · 1881 words

Multi-Analyte Biomarker Panels for Neurodegeneration

diagnostic · 1721 words

Advanced Proteomics and Protein Biomarker Panels in CBS/PSP

therapeutic · 1602 words

Cerebrospinal Fluid (CSF) Biomarker Panels

biomarker · 1515 words

Outgoing (1)

TargetRelationTypeStr
Alzheimer'S Diseasebiomarker_fordisease0.90

Incoming (3)

SourceRelationTypeStr
22801742achievespaper0.90
22801742achieves in AIBL cohortpaper0.90
22801742attains in ADNI cohortpaper0.90

Targeting Hypotheses (5)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
Integrated Biomarker Panel for Therapeutic Window Identifica 0.784 neurodegeneration What are the precise temporal dynamics o
Neurovascular Permeability Score (NVPS): Composite Plasma + 0.600 - Blood-brain barrier permeability changes
Dynamic Microglial Phenotype Switching Biomarker Panel for N 0.577 neurodegeneration What amyloid threshold level is required
GrimAge Acceleration as a Cell-Type-Resolved CSF Biomarker P 0.369 - Epigenetic clocks as biomarkers for Alzh
Sex-Specific Metabolic Biomarker Panels for Alzheimer's Ther 0.000 - Which metabolic biomarkers can distingui

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (2)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
Chi3l1 deletion effects on baseline glial activation in mice validation baseline neuroinflammation 0.900 0.00 Chi3l1 knockout mice proposed N/A
CHI3L1 variant association with AD progression in human patients exploratory Alzheimer's disease 0.850 0.00 human patients proposed N/A

Related Papers (20)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis [PMID:40771159] Padilla CM, Lafyatis R, Gibson KF, Morse Arthritis Care Res (Hoboken) 2026 0
Obstructive sleep apnea, biomarker profiles, and clinical progression in Parkins [PMID:41499940] Zhu S, An D, Liu X Sleep Med 2026 0
SuPAR levels are increased in sera of euthymic patients with bipolar disorder an [PMID:41605346] Kök Kendirlioğlu B, Çörekli Kaymakçı E, J Affect Disord 2026 0
Chitinase-like Proteins YKL-40 and YKL-39 in Colorectal Cancer. [PMID:41677627] Ivanova T, Kazakova M, Dikov D, Dzhambov Cells 2026 0
Correction: CHI3L1: An Emerging Player in Neuroinflammation and Neurodegeneratio [PMID:41699333] Mushtaq Umar; Seh Bilal Ahmad; Khanday F Molecular Neurobiology 2026 0
Association of Alzheimer's disease progression with YKL40 levels in peripheral b [PMID:41725729] Yang Q, Wang R, Pei J, Fu Q, Zhan Y et a Front Neurol 2026 0
Constitutive neuronal expression and disease-associated upregulation of chitinas [PMID:41762671] Gaur N, Angerer C, Gunes ZI, Ancau M, Wa Brain 2026 0
Plasma CHI3L1 as a marker of cognitive and structural brain changes in radiologi [PMID:41953284] Schneider R, Brand-Arzamendi K, Lim TR, BMJ Neurol Open 2026 0
Association of CSF α-synuclein seed amplification assay positivity with disease [PMID:39428831] Tosun, Hausle, Thropp, Concha-Marambio, Alzheimer's & dementia : the j 2025 0
CSF markers of vascular injury correlate with tau and cognitive decline in early [PMID:41319164] Miners, Roy, Love Alzheimer's & dementia : the j 2025 0
Association of CSF α-synuclein seed amplification assay positivity with disease [PMID:39428831] Unknown Alzheimer's & dementia : the j 2025 0
CSF markers of vascular injury correlate with tau and cognitive decline in early [PMID:41319164] Unknown Alzheimer's & dementia : the j 2025 0
Sex Differences in Alzheimer's Disease. [PMID:37030962] Aggarwal, Mielke Neurologic clinics 2023 0
Sex Differences in Alzheimer's Disease. [PMID:37030962] Unknown Neurologic clinics 2023 0
DunedinPACE, a DNA methylation biomarker of the pace of aging. [PMID:35029144] Belsky DW, Caspi A, Corcoran DL Elife 2022 0
Epigenetic GrimAge acceleration and cognitive impairment in bipolar disorder. [PMID:35810614] Lima CNC, Suchting R, Scaini G Eur Neuropsychopharmacol 2022 0
Epigenetic clock: A promising biomarker and practical tool in aging. [PMID:36206857] Duan R, Fu Q, Sun Y Ageing Res Rev 2022 0
DNA methylation GrimAge version 2. [PMID:36516495] Lu AT, Binder AM, Zhang J Aging (Albany NY) 2022 0
CSF tau microtubule binding region identifies tau tangle and clinical stages of [PMID:33283854] Horie K, Barthélemy NR, Sato C, Bateman Brain : a journal of neurology 2021 0
CSF tau microtubule binding region identifies tau tangle and clinical stages of [PMID:33283854] Horie K, Barthélemy NR, Sato C, Bateman Brain : a journal of neurology 2021 0

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning Biomarker Panel in their description or question text

No additional research found