gene

AURKC

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about AURKC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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Summary

Gene page for AURKC encoding a serine/threonine kinase essential for meiosis and cell division

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🧬 Gene Info

Gene Symbol	AURKC
Full Name	Aurora Kinase C
Chromosome	19q13.43
Protein Family	Aurora kinase family (serine/threonine kinases)
Protein Type	Serine/Threonine Kinase
Function	is a serine/threonine kinase that plays essential roles in cell division, particularly during meiosis.
Primary Expression	testis and ovaries, alterations in Aurora kinase signaling have been noted in neurodegenerative conditions, where cell cycle dysregulation is a recogn
Amino Acids	309 aa
UniProt ID	Q96GF4
NCBI Gene ID	6795
Ensembl ID	ENSG00000171495
OMIM	604615
GeneCards	AURKC
Human Protein Atlas	AURKC
N-terminal domain	Regulatory domain controlling kinase activity
Associated Diseases	Male Infertility, Oocyte Aneuploidy, Cancer
Databases	GeneCards HPA STRING

🔮 Predicted Structure: AURKC — AlphaFold Q96GF4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

AURKC — Aurora Kinase C

gene · 1072 words

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AURKC Protein

protein · 2291 words

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Pathway Diagram

graph TD
    AURKC["AURKC"]
    style AURKC fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff
    neurodegeneration["neurodegeneration"]

    AURKC -->|"implicated_in"| neurodegeneration

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef drug fill:#1a2a2a,stroke:#80cbc4,color:#e0e0e0
    class neurodegeneration disease

Outgoing (0)

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No outgoing edges

Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning AURKC in their description or question text

No additional research found