Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ANT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | SLC25A4 |
| Full Name | Solute Carrier Family 25 Member 4 |
| Chromosome | 4q34.3 |
| Function | SLC25A4 (ANT1) is a mitochondrial carrier protein that exchanges mitochondrial ATP for cytosolic ADP. |
| Molecular Weight | 33 kDa |
| Amino Acids | 326 aa |
| UniProt ID | P12235 |
| NCBI Gene ID | 291 |
| Ensembl ID | ENSG00000151729 |
| OMIM | 103220 |
| GeneCards | SLC25A4 |
| Human Protein Atlas | SLC25A4 |
| ATP export | Exchanges mitochondrial ATP for ADP |
| Cellular energy | Critical for ATP production and export |
| ROS production | Modulates mitochondrial reactive oxygen species |
| Associated Diseases | neurodegeneration |
| KG Connections | 3 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
ANT1(["ANT1"])
mRNA_levels["mRNA levels"]
protein_levels["protein levels"]
Src["Src"]
neurodegeneration["neurodegeneration"]
ANT1 -->|"upregulates"| mRNA_levels
ANT1 -->|"upregulates"| protein_levels
Src -->|"phosphorylates"| ANT1
ANT1 -->|"implicated in"| neurodegeneration
style ANT1 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff| Target | Relation | Type | Str |
|---|---|---|---|
| mRNA levels | upregulates | entity | 0.80 |
| protein levels | upregulates | entity | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Src | phosphorylates | enzyme | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ANT1 in their description or question text
No additional research found