Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about AD_hippocampus: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| ubiquitinated_proteins | accumulates_in | mechanism | 0.50 |
| VPS35 | reduced_in | gene | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| VEGF-family genetic control of vascular-neuronal coupling in | 0.626 | neurodegeneration | VEGF Family GWAS Signals and Cerebrovasc |
| Cell-state stratification is required to resolve VEGF Family | 0.612 | neurodegeneration | VEGF Family GWAS Signals and Cerebrovasc |
| Perturbation-first validation should precede therapeutic cla | 0.608 | neurodegeneration | VEGF Family GWAS Signals and Cerebrovasc |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-27 | 3 hypotheses Top: 0.626
proteomics | 2026-04-16 | 19 hypotheses Top: 0.591
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
active · Rounds: 4 · Score: 0.67 · 2026-04-28
closed · Rounds: 4 · Score: 0.50 · 2026-04-18
Hypotheses and analyses mentioning AD_hippocampus in their description or question text
No additional research found