ABI3

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolABI3
NameABI family member 3
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provid

107Connections

This is an externally resolved entity

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