protein

5-HT2A RECEPTOR

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about 5-HT2A RECEPTOR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections
0Hypotheses
1Analyses
1Outgoing
1Incoming
0Experiments
1Debates

Summary

Comprehensive review of the serotonin 2A receptor (HTR2A) in neurodegenerative diseases including Alzheimer's and Parkinson's disease, with focus on molecular mechanisms, therapeutic targeting, and clinical evidence

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🔬 Protein Info
Gene Symbol5-HT2A RECEPTOR
AliasesHTR2A
Chromosome13q14
Molecular Weight53 kDa
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Pathway Diagram

graph TD
    A["Gene expression"] --> B["5 HT2A RECEPTOR"]
    B --> C["Protein folding and
quality control"] B --> D["Cellular signaling"] C --> E["Proteostasis"] D --> F["Neurotoxicity"] E --> G["Disease outcome"] F --> G classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0 classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0 classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0 class B protein class G disease

Outgoing (1)

TargetRelationTypeStr
BDNF releaseinhibitsprocess0.70

Incoming (1)

SourceRelationTypeStr
Trazodoneinhibitsdrug0.90

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

What is the minimum effective dose of trazodone required for disease-modifying e

neurodegeneration | 2026-04-26 | 7 hypotheses Top: 0.605

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (1)

Multi-agent debates referencing this entity

What is the minimum effective dose of trazodone required for disease-modifying e

closed · Rounds: 4 · Score: 1.00 · 2026-04-26

Related Research

Hypotheses and analyses mentioning 5-HT2A RECEPTOR in their description or question text

No additional research found