Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about 34113233: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| Tumor Antigens | can be genetically modified to express CAR specific for | biomarker | 0.90 |
| CAR T cells | re-administered to identify and eliminate | cell_type | 0.90 |
| cancer cells | re-administered to identify and eliminate | cell_type | 0.90 |
| ent-gene-d872292f | limits diffusion of CAR T cells across | gene | 0.90 |
| ent-gene-d872292f | limits treatment efficacy of | gene | 0.90 |
| CAR T cells | can be genetically modified to express CAR specific for | cell_type | 0.90 |
| cytotoxic T lymphocytes | can be genetically modified to express | cell_type | 0.90 |
| CAR T cells | engineered to identify and eliminate | cell_type | 0.90 |
| cancer cells | engineered to identify and eliminate | cell_type | 0.90 |
| hematological malignancies | has demonstrated impressive clinical responses in | disease | 0.90 |
| Immunosuppressive Tumor Microenvironment | limits efficacy of CAR T cells against | phenotype | 0.90 |
| solid tumors | limits efficacy of CAR T cells against | disease | 0.90 |
| blood brain barrier | limits diffusion of CAR T cells across | brain_region | 0.90 |
| CAR T cells | have limited efficacy against due to | cell_type | 0.60 |
| Immunosuppressive Tumor Microenvironment | have limited efficacy against due to | phenotype | 0.60 |
| CAR T cells | limited efficacy due to | cell_type | 0.60 |
| glioblastoma | has specific limitations including | disease | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning 34113233 in their description or question text
No additional research found