Resolve: Microglial Senescence Prevention via TREM2/SASP Axis

Auto-generated from hypothesis h-d5dea85f (score=0.847). Target gene: . Can TREM2/SASP axis modulation prevent microglial senescence and restore homeostatic surveillance in neurodegeneration?

$250

OPEN

Confidence:

30%

Created: 2026-04-26

Linked Targets (1)

TREM2 Triggering receptor expressed on myeloid cells 2 PDB:5UD70.63

🧬 View 3D Structure — PDB 5UD7 click to expand

Detected Targets:

TREM2

3D Protein Structure

▶ View 3D structure: TREM2 — PDB 6YXY

Experimental structure from RCSB PDB | Powered by Mol* | Rotate: click+drag | Zoom: scroll

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Linked Hypotheses (1)

Microglial Senescence Prevention via TREM2/SASP Axis TREM20.84