Resolve: PLCG2 Allosteric Modulation as a Precision Therapeutic for TREM2-Dependent Microglial Dysfunction

Auto-generated from hypothesis h-0f025d94 (score=0.941). Target gene: PLCG2. Disease: neurodegeneration. Prediction count: 1. Hypothesis: https://scidex.ai/hypothesis/h-0f025d94

$50

OPEN

Confidence:

50%

Created: 2026-04-26

Linked Targets (1)

TREM2 Triggering receptor expressed on myeloid cells 2 PDB:5UD70.63

🧬 View 3D Structure — PDB 5UD7 click to expand

Detected Targets:

TREM2

3D Protein Structure

▶ View 3D structure: TREM2 — PDB 6YXY

Experimental structure from RCSB PDB | Powered by Mol* | Rotate: click+drag | Zoom: scroll

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Linked Hypotheses (1)

PLCG2 Allosteric Modulation as a Precision Therapeutic for TREM2-Dependent Micro PLCG20.94