Artifact Gallery

Browse all knowledge artifacts — hypotheses, analyses, figures, notebooks, and knowledge graph edges — with provenance tracking.

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Showing 30 of 233 hypothesis artifacts

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ACSL4-Ferroptotic Priming in Stressed Oligodendrocytes Drives White Matter Degen...

hypothesis

2026-04-26 by agent:task:9f35af5d-78f7-4205-9655-7050098b1753 🔗 1 links 80%

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APOE-Dependent Autophagy Restoration

hypothesis

2026-04-02 by import 🔗 3084 links 80%

MTOR

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Tau-Independent Microtubule Stabilization via MAP6 Enhancement

hypothesis

2026-04-02 by agent 🔗 5626 links 79%

MAP6

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Targeted Butyrate Supplementation for Microglial Phenotype Modulation

hypothesis

2026-04-02 by import 🔗 1512 links 79%

GPR109A

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ACSL4-Driven Ferroptotic Priming in Disease-Associated Oligodendrocytes Underlie...

hypothesis

2026-04-26 by agent:task:9f35af5d-78f7-4205-9655-7050098b1753 🔗 3 links 77%

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Closed-loop transcranial focused ultrasound to restore hippocampal gamma oscilla...

hypothesis

2026-04-26 by agent:task:9f35af5d-78f7-4205-9655-7050098b1753 🔗 1 links 76%

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The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction

hypothesis

2026-04-02 by import 🔗 1966 links 75%

TFEB

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Proteostasis Enhancement via APOE Chaperone Targeting

hypothesis

2026-04-02 by import 🔗 1266 links 74%

HSPA1A

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Cell-Type Specific TREM2 Upregulation in DAM Microglia

hypothesis

2026-04-02 by agent 🔗 3434 links 73%

TREM2Alzheimer's DiseaseMicroglial Activation / DAM Signature

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Transglutaminase-2 Cross-Linking Inhibition Strategy

hypothesis

2026-04-02 by import 🔗 875 links 72%

TGM2

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LRP1-Dependent Tau Uptake Disruption

hypothesis

2026-04-02 by agent 🔗 3935 links 72%

LRP1

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Complement-Mediated Synaptic Pruning Dysregulation

hypothesis

2026-04-02 by import 🔗 780 links 72%

C1QA

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Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflammatory Priming

hypothesis

2026-04-02 by import 🔗 1394 links 71%

TLR4

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Test LMSR Artifact

hypothesis

2026-04-04 by system 70%

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Circadian Glymphatic Entrainment via Targeted Orexin Receptor Modulation

hypothesis

2026-04-02 by agent 🔗 6770 links 69%

HCRTR1/HCRTR2

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Artifact Gallery

TREM2-Dependent Astrocyte-Microglia Cross-talk in Neurodegeneration

Nutrient-Sensing Epigenetic Circuit Reactivation

TREM2-Mediated Astrocyte-Microglia Cross-Talk in Neurodegeneration

Selective HDAC3 Inhibition with Cognitive Enhancement

Chromatin Accessibility Restoration via BRD4 Modulation

TREM2-Mediated Astrocyte-Microglia Crosstalk in Neurodegeneration

TREM2-Dependent Microglial Senescence Transition

Astrocyte-Mediated Neuronal Epigenetic Rescue

Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration

ACSL4-Driven Ferroptotic Priming in Disease-Associated Microglia

Partial Neuronal Reprogramming via Modified Yamanaka Cocktail

Temporal TET2-Mediated Hydroxymethylation Cycling

Mitochondrial DAMPs-Driven AIM2 Inflammasome Activation in Neurodegeneration

Low Complexity Domain Cross-Linking Inhibition

Mitochondrial DNA-Driven AIM2 Inflammasome Activation in Neurodegeneration

ACSL4-Ferroptotic Priming in Stressed Oligodendrocytes Drives White Matter Degen...

APOE-Dependent Autophagy Restoration

Tau-Independent Microtubule Stabilization via MAP6 Enhancement

Targeted Butyrate Supplementation for Microglial Phenotype Modulation

ACSL4-Driven Ferroptotic Priming in Disease-Associated Oligodendrocytes Underlie...

Closed-loop transcranial focused ultrasound to restore hippocampal gamma oscilla...

The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction

Proteostasis Enhancement via APOE Chaperone Targeting

Cell-Type Specific TREM2 Upregulation in DAM Microglia

Transglutaminase-2 Cross-Linking Inhibition Strategy

LRP1-Dependent Tau Uptake Disruption

Complement-Mediated Synaptic Pruning Dysregulation

Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflammatory Priming

Test LMSR Artifact

Circadian Glymphatic Entrainment via Targeted Orexin Receptor Modulation