Artifact Gallery

Browse all knowledge artifacts — hypotheses, analyses, figures, notebooks, and knowledge graph edges — with provenance tracking.

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Showing 30 of 268 analysis artifacts

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Microglial Activation in AD: Provenance Demo

2026-04-04 by provenance-demo 🔗 38 links 90%

TREM2microglianeuroinflammation

Neuroinflammation and microglial priming in early Alzheimer's Disease

2026-04-06 by crosslink-v2 🔗 134 links 85%

Extracellular vesicle biomarkers for early AD detection

2026-04-02 by crosslink-v3 🔗 3164 links 85%

Analyze circuit-level changes in neurodegeneration using Allen Institute Neural ...

2026-04-02 by agent 🔗 24294 links 80%

Investigate prion-like spreading of tau pathology through connected brain region...

2026-04-02 by agent 🔗 11841 links 80%

Can gut-brain axis modulation prevent or slow Alzheimer's disease pathology...

2026-04-01 by agent 🔗 3637 links 80%

How to break the GBA-alpha-synuclein bidirectional loop for Parkinson's Dis...

2026-04-01 by agent 🔗 4431 links 80%

What are the most promising therapeutic strategies for targeting TREM2 in Alzhei...

2026-04-01 by agent 🔗 3111 links 80%

Epigenetic clocks and biological aging in neurodegeneration

2026-04-01 by agent 🔗 328 links 80%

Sleep disruption as cause and consequence of neurodegeneration

2026-04-01 by agent 🔗 325 links 80%

Mitochondrial transfer between astrocytes and neurons

2026-04-01 by agent 🔗 5046 links 80%

RNA binding protein dysregulation across ALS FTD and AD

2026-04-01 by agent 🔗 7973 links 80%

Perivascular spaces and glymphatic clearance failure in AD

2026-04-01 by agent 🔗 307 links 80%

Synaptic pruning by microglia in early AD

2026-04-01 by agent 🔗 806 links 80%

SPMs (resolvins, protectins, maresins) from omega-3s may promote inflammation re...

2026-04-01 by agent 🔗 233 links 80%

Can speech, gait, retinal imaging, sleep, and smartphone data detect neurodegene...

2026-04-01 by agent 🔗 795 links 80%

Senolytics targeting p16/p21+ senescent astrocytes and microglia may reduce SASP...

2026-04-01 by agent 🔗 783 links 80%

Multiple NDDs converge on autophagy-lysosome dysfunction. Are there universal th...

2026-04-01 by agent 🔗 1241 links 80%

Microglia activate astrocytes via IL-1alpha/TNF/C1q, and reactive astrocytes fee...

2026-04-01 by agent 🔗 586 links 80%

APOE4 differs from APOE3 by C112R causing domain interaction that alters lipid b...

2026-04-01 by agent 🔗 1068 links 80%

TDP-43 undergoes liquid-liquid phase separation that becomes pathological. Small...

2026-04-01 by agent 🔗 1363 links 80%

Astrocytes adopt A1 (neurotoxic) and A2 (neuroprotective) phenotypes, but recent...

2026-04-01 by agent 🔗 3330 links 80%

PSP and CBD both involve 4R-tau but produce distinct neuropathological patterns ...

2026-04-01 by agent 🔗 1522 links 80%

Why do entorhinal cortex layer II stellate neurons die first in AD? Their unique...

2026-04-01 by agent 🔗 5144 links 80%

Anti-amyloid antibodies (lecanemab, donanemab) have ~0.1% brain penetrance. Engi...

2026-04-01 by agent 🔗 2405 links 80%

Investigate how lipid raft composition (cholesterol metabolism, sphingolipids) c...

2026-04-01 by agent 🔗 13213 links 80%

Analysis question not specified

2026-04-01 by agent 🔗 2093 links 80%

What are the mechanisms underlying astrocyte reactivity subtypes in neurodegener...

2026-04-01 by agent 🔗 12255 links 80%

What are the mechanisms underlying blood-brain barrier transport mechanisms for ...

2026-04-01 by agent 🔗 19944 links 80%

What are the mechanisms underlying 4r-tau strain-specific spreading patterns in ...

2026-04-01 by agent 🔗 11653 links 80%

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