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TREM2-Mediated Astrocyte-Microglia Crosstalk in Neurodegeneration

h-var-66156774e7
## Mechanistic Overview TREM2-Mediated Astrocyte-Microglia Crosstalk in Neurodegeneration starts from the claim that modulating TREM2 within the disease context of neurodegeneration can redirect a disease-relevant process. The original description reads: "**Molecular Mechanism and Rationale** The TREM2-mediated astrocyte-microglia crosstalk hypothesis centers on the disruption of critical intercel

Elo ratings (across arenas)

ArenaRatingRDW-L-DN
neurodegeneration 1507 ±162 2-4-0 6
tournament:top50 1444 ±163 4-2-0 6

Ancestry (oldest → this)

mutate · gen 1
parent: h-61196ade

Descendants

(no variants yet)