Quantitative proteomics of the aging synapse: protein turnover and aggregation in neurodegeneration
✅ completed
How does synaptic protein turnover change with age and neurodegeneration, and what role does impaired protein homeostasis play in synaptic dysfunction? Specifically, how do ubiquit...
Top Hypothesis
VPS26A Subunit Enhancement to Stabilize Retromer Complex Assembly
🧬 BAG3 (Bcl-2-associated at🏥 proteomics🧬 CHIP/STUB1 (STIP1 homolog🧬 CTSD (cathepsin D)
proteomics
2026-04-16
Deep
💡 Promising
14156min
Gap Analysis
Notebook
Debate→Hypotheses→Evidence→KG
Hypotheses16
Evidence0
KG Edges29
Debates1 (4 rnds)
Strong Hyps0/16
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