[Demo] Add Mol* 3D protein viewer to hypothesis detail pages

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Goal

Embed Mol (molstar) 3D protein structure viewer on hypothesis detail pages for target proteins. Load the task-specified PDB structures: LRP1 (2FCW), TREM2 (6YXY), APOE (2L7B), CYP46A1 (2Q9F), SMPD1 (5I73). Mol viewer should appear below hypothesis description and NOT be featured on /showcase.

Acceptance Criteria

☑ Mol* 3D viewer embedded in hypothesis_detail() route (/hypothesis/{id})
☑ Viewer appears below hypothesis description (collapsible lazy-load panel)
☑ Task-specified PDB IDs used: LRP1=2FCW, TREM2=6YXY, APOE=2L7B, CYP46A1=2Q9F, SMPD1=5I73
☑ PDB IDs in hypothesis page consistent with entity and challenge pages
☑ Mol* viewer NOT shown on /showcase page
☑ PDBe Mol* CDN used (https://www.ebi.ac.uk/pdbe/pdb-component-library/)
☑ AlphaFold fallback for genes without experimental structures

Approach

  • Find the pdb_mapping dict in hypothesis_detail() function (~line 35693)
  • Update stale PDB IDs to match task spec and other detail pages:
  • - TREM2: 5UD7 → 6YXY (TREM2 ectodomain crystal structure)
    - LRP1: 1CR8 → 2FCW (LRP1 complement-type repeat domain)
    - SMPD1: 5I85 → 5I73 (SMPD1 crystal structure)
  • Verify entity_detail() and challenge_detail() already use correct IDs (they do)
  • Create spec, test API, commit
  • Dependencies

    • Prior work: 062cdfd65 — original Mol* embed implementation
    • Prior work: 91ec0016e — Mol* removed from /showcase

    Work Log

    2026-04-24 — Slot claude-auto:41

    • Read AGENTS.md and task spec
    • Observed Mol* viewer already in api.py on main (hypothesis_detail, entity_detail, challenge_detail)
    • Found PDB ID inconsistency: hypothesis page used 5UD7/1CR8/5I85 while entity/challenge pages used 6YXY/2FCW/5I73
    • Updated pdb_mapping in hypothesis_detail() at line 35695-35696: TREM2→6YXY, LRP1→2FCW, SMPD1→5I73
    • All three pages now use identical PDB IDs for the task-specified proteins
    • No old stale IDs (5UD7/1CR8/5I85) remain in codebase
    • Result: hypothesis detail pages now show correct PDB structures matching task spec

    File: d16_04_BC3E8EEA_mol_3d_protein_viewer_hypothesis_spec.md
    Modified: 2026-04-24 08:44
    Size: 2.1 KB