[Wiki] Add mermaid pathway diagrams to top 5 mechanism/disease wiki pages

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[Wiki] Add mermaid pathway diagrams to top 5 mechanism/disease wiki pages

ID: 372681b3-cc0 Priority: 88 Type: one_shot Status: open

Goal

[Wiki] Add mermaid pathway diagrams to top 5 mechanism/disease wiki pages

Acceptance Criteria

☑ Concrete deliverables created
☑ Work log updated with timestamped entry

Work Log

  • 2026-04-20T23:10:00Z — Added mermaid pathway diagrams to top 5 mechanism/disease wiki pages:
1. mechanisms-ad-mechanism-index (5834 words) — AD pathway cascade diagram (amyloid → tau → neuroinflammation → mitochondrial dysfunction → oxidative stress → synaptic failure → neuronal death)
2. diseases-caregiver-support-palliative-care-cbs-psp (3381 words) — CBS/PSP disease progression and caregiver journey diagram
3. mechanisms-ftd-ion-channel-dysfunction (3283 words) — FTD ion channel dysfunction pathway (proteinopathy → ion dysregulation → excitotoxicity → network dysfunction → atrophy)
4. mechanisms-als-combination-therapy-matrix (3214 words) — ALS combination therapy matrix showing RNA dysregulation, protein aggregation, excitotoxicity, oxidative stress, mitochondrial dysfunction, and FDA-approved therapies (riluzole, edaravone, AMX0035, tofersen)
5. mechanisms-dashboard (3194 words) — Neurodegenerative mechanisms overview diagram (protein misfolding, senescence, neuroinflammation, oxidative stress, mitochondrial dysfunction → AD/PD/ALS)
- Diagrams verified present in wiki_pages.content_md via PostgreSQL query
- Task ID: 372681b3-cc0b-4a32-826a-eaffbc643f83

Tasks using this spec (1)
[Wiki] Add mermaid pathway diagrams to top 5 mechanism/disea
Wiki done P88
File: 372681b3_cc0_spec.md
Modified: 2026-04-25 23:40
Size: 1.6 KB