Regenerative nanomedicine for vision restoration.

Zarbin MA, Arlow T, Ritch R

Mayo Clin Proc 2013

1. Mayo Clin Proc. 2013 Dec;88(12):1480-90. doi: 10.1016/j.mayocp.2013.05.025. Regenerative nanomedicine for vision restoration. Zarbin MA(1), Arlow T, Ritch R. Author information: (1)Institute of Ophthalmology and Visual Science, New Jersey Medical School, Rutgers University, Newark, NJ. Electronic address: zarbin@rutgers.edu. Herein, we discuss recent applications of nanotechnology to ophthalmology, including nanoparticles for drug, gene, and trophic factor delivery; regenerative medicine (in the areas of optogenetics and optic nerve regeneration); and diagnostics (eg, minimally invasive biometric monitoring). Specific applications for the management of choroidal neovascularization, retinal neovascularization, oxidative damage, optic nerve damage, and retinal degenerative disease are considered. Nanotechnology will play an important role in early- and late-stage interventions in the management of blinding diseases. Copyright © 2013 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved. DOI: 10.1016/j.mayocp.2013.05.025 PMID: 24290123 [Indexed for MEDLINE]