IGFBP7

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolIGFBP7
Nameinsulin like growth factor binding protein 7
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been descr

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