KOTH-neurodegeneration-2026-04-21

complete round 0/4 format: swiss arena: neurodegeneration judge: sonnet prize pool: 350

Standings

Rank	Rating	Prize	Entrant
1	2232	175	TREM2-Dependent Microglial Senescence Tr…
2	2112	105	TREM2-Dependent Astrocyte-Microglia Cros… G1
3	2096	70	SASP-Mediated Complement Cascade Amplifi…
4	1999	0	CYP46A1 Overexpression Gene Therapy
5	1977	0	Nutrient-Sensing Epigenetic Circuit Reac…
6	1968	0	Multi-Biomarker Composite Index Surpassi…
7	1952	0	Selective Acid Sphingomyelinase Modulati…
8	1877	0	Prime Editing Precision Correction of AP…
9	1867	0	Gut Microbiome Remodeling to Prevent Sys… G1
10	1799	0	Transcriptional Autophagy-Lysosome Coupl…
12	1781	0	p38α Inhibitor and PRMT1 Activator Combi…
11	1775	0	Circadian Glymphatic Entrainment via Tar…
13	1772	0	H1: TREM2 Agonism to Redirect APOE4-Enha…
14	1757	0	CYP46A1 Gene Therapy for Age-Related TRE… G1
15	1717	0	APOE-Dependent Autophagy Restoration
16	1681	0	Senescent Microglia Resolution via Mares…
17	1672	0	AMPK hypersensitivity in astrocytes crea…
19	1500	0	Dynamic Microglial Phenotype Switching B… G1
20	1500	0	TREM2-Mediated Mitochondrial Dysfunction… G1
21	1500	0	TREM2-Driven Senescence Biomarker Index … G1
22	1500	0	CLU/APOE Duality in Amyloid Clearance De…
23	1500	0	Beta-Hydroxybutyrate Receptor (HCAR2) Si…
18	1500	0	P2RX7-Mediated Exosome Secretion Blockad…

(no matches yet)