% Bibliography for hypothesis h_seaad_001
% Title: Microglial TREM2 downregulation impairs damage-associated response in late-stage Alzheimer's disease
% Generated: 2026-04-28T17:27:52Z

@article{pmid41109213,
  title = {The gain-of-function TREM2-T96K mutation increases risk for Alzheimer's disease by impairing microglial function.},
  author = {Pilat DJ, Le H, Prokopenko D, Lin CJ, Eimer WA et al.},
  journal = {Neuron},
  year = {2026},
  pmid = {41109213},
  doi = {doi: 10.1016/j.neuron.2025.09.032},
  url = {https://pubmed.ncbi.nlm.nih.gov/41109213/},
}

@article{pmid41213496,
  title = {Role of TREM2 in neuroinflammation.},
  author = {Abdulkhaliq AA, Alasiri G, Almoghrabi Y, Kim B, Khan J et al.},
  journal = {Exp Neurol},
  year = {2026},
  pmid = {41213496},
  doi = {doi: 10.1016/j.expneurol.2025.115547},
  url = {https://pubmed.ncbi.nlm.nih.gov/41213496/},
}

@article{pmid41365298,
  title = {A dysregulated hepcidin-iron axis impairs antiviral immunity and induces lethal liver pathology in neonates.},
  author = {Xu Y, Chen X, Fang R, Wang X, Zhang Y et al.},
  journal = {Immunity},
  year = {2026},
  pmid = {41365298},
  doi = {doi: 10.1016/j.immuni.2025.11.001},
  url = {https://pubmed.ncbi.nlm.nih.gov/41365298/},
}

@article{pmid41494649,
  title = {Synergistic potential of TREM2 agonists and exercise training in Alzheimer's disease.},
  author = {Zhang J, St Pierre Schneider B, Muguerza E, Chung E, Hsu CG},
  journal = {Am J Physiol Endocrinol Metab},
  year = {2026},
  pmid = {41494649},
  doi = {doi: 10.1152/ajpendo.00124.2025},
  url = {https://pubmed.ncbi.nlm.nih.gov/41494649/},
}

@article{pmid41576929,
  title = {Armored macrophage-targeted CAR-T cells reset and reprogram the tumor microenvironment and control metastatic cancer growth.},
  author = {Mateus-Tique J, Lakshmi A, Singh B, Iyer R, Sánchez-Paulete AR et al.},
  journal = {Cancer Cell},
  year = {2026},
  pmid = {41576929},
  doi = {doi: 10.1016/j.ccell.2025.12.021},
  url = {https://pubmed.ncbi.nlm.nih.gov/41576929/},
}

@article{pmid41576952,
  title = {Peripheral cancer attenuates amyloid pathology in Alzheimer's disease via cystatin-c activation of TREM2.},
  author = {Li X, Tang X, Zeng J, Duan L, Hou Z et al.},
  journal = {Cell},
  year = {2026},
  pmid = {41576952},
  doi = {doi: 10.1016/j.cell.2025.12.020},
  url = {https://pubmed.ncbi.nlm.nih.gov/41576952/},
}

@article{pmid41580393,
  title = {TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism.},
  author = {Feiten AF, Dahm K, Schlepckow K, van Lengerich B, Suh JH et al.},
  journal = {Nat Commun},
  year = {2026},
  pmid = {41580393},
  doi = {doi: 10.1038/s41467-026-68706-8},
  url = {https://pubmed.ncbi.nlm.nih.gov/41580393/},
}

@article{pmid41720086,
  title = {Dissecting genetic and immune drivers of heterogeneous responses to neoadjuvant immunochemotherapy in gastric cancer.},
  author = {Zhao Q, Huang R, Wang C, Hu J, Nie R et al.},
  journal = {Cancer Cell},
  year = {2026},
  pmid = {41720086},
  doi = {pii: S1535-6108(26)00054-1. doi: 10.1016/j.ccell.2026.01.015},
  url = {https://pubmed.ncbi.nlm.nih.gov/41720086/},
}

@article{pmid41745721,
  title = {Alzheimer's Disease as a Disorder of Neuroimmune Dysregulation.},
  author = {Aranda-Abreu GE, Rojas-Durán F, Hernández-Aguilar ME, Herrera-Covarrubias D, Tlapa-Monge LR, Mestizo-Gutiérrez SL},
  journal = {Neurology international},
  year = {2026},
  pmid = {41745721},
  doi = {10.3390/neurolint18020037},
  url = {https://pubmed.ncbi.nlm.nih.gov/41745721/},
}

@article{pmid41792456,
  title = {TREM2 in neurodegeneration and diseases.},
  author = {["Abdulkhaliq A", "Alasiri G", "Kim B", "Khan J", "Ajoolabady A", "Yousof S", "Ren J", "Tuomilehto J", "Borai A", "Alrfaei B"]},
  journal = {Molecular psychiatry},
  year = {2026},
  pmid = {41792456},
  doi = {10.1038/s41380-026-03505-7},
}

@article{pmid41907842,
  title = {Molecular mechanism of Alzheimer's disease using integrated multi-omics.},
  author = {Alhusaini M, Mussa BM, Ilce BY, Alhaj H, Hamoudi R},
  journal = {Frontiers in aging neuroscience},
  year = {2026},
  pmid = {41907842},
  doi = {10.3389/fnagi.2026.1735696},
  url = {https://pubmed.ncbi.nlm.nih.gov/41907842/},
}

@article{pmid41585268,
  title = {Viral and non-viral cellular therapies for neurodegeneration.},
  author = {["Srivastav Jyotsna", "Sharma Sachin"]},
  journal = {Frontiers in medicine},
  year = {2025},
  pmid = {41585268},
  doi = {10.1016/j.addr.2021.113834},
}