% Bibliography for hypothesis h-var-a0933e666d % Title: Microglial AIM2 Inflammasome as the Primary Driver of TDP-43 Proteinopathy Neuroinflammation in ALS/FTD % Generated: 2026-04-28T20:42:36Z @article{pmid36652438, title = {Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes.}, author = {Hegdekar N, Sarkar C, Bustos S, Ritzel RM, Hanscom M, Ravishankar P, Philkana D, Wu J, Loane DJ, Lipinski MM}, journal = {Autophagy}, year = {2023}, pmid = {36652438}, doi = {10.1080/15548627.2023.2167689}, url = {https://pubmed.ncbi.nlm.nih.gov/36652438/}, } @article{pmid37633753, title = {Inflammasome assembly in neurodegenerative diseases.}, author = {Singh J, Habean ML, Panicker N}, journal = {Trends in neurosciences}, year = {2023}, pmid = {37633753}, doi = {10.1016/j.tins.2023.07.009}, url = {https://pubmed.ncbi.nlm.nih.gov/37633753/}, } @article{pmid34877938, title = {NLRP3/caspase-1/GSDMD-mediated pyroptosis exerts a crucial role in astrocyte pathological injury in mouse model of depression.}, author = {Li S, Sun Y, Song M, Song Y, Fang Y, Zhang Q, Li X, Song N, Ding J, Lu M, Hu G}, journal = {JCI insight}, year = {2021}, pmid = {34877938}, doi = {10.1172/jci.insight.146852}, url = {https://pubmed.ncbi.nlm.nih.gov/34877938/}, } @article{pmid30966861, title = {Small molecule-driven NLRP3 inflammation inhibition via interplay between ubiquitination and autophagy: implications for Parkinson disease.}, author = {["Han X", "Sun S", "Sun Y", "Song Q", "Zhu J", "Song N", "Chen M", "Sun T", "Xia M", "Ding J", "Lu M", "Yao H", "Hu G"]}, journal = {Autophagy}, year = {2020}, pmid = {30966861}, doi = {10.1080/15548627.2019.1596481}, url = {https://pubmed.ncbi.nlm.nih.gov/30966861/}, } @article{pmid30381407, title = {Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice.}, author = {Gordon R, Albornoz EA, Christie DC, Langley MR, Kumar V, Mantovani S, Robertson AAB, Butler MS, Rowe DB, O'Neill LA, Kanthasamy AG, Schroder K, Cooper MA, Woodruff TM}, journal = {Science translational medicine}, year = {2018}, pmid = {30381407}, doi = {10.1126/scitranslmed.aah4066}, url = {https://pubmed.ncbi.nlm.nih.gov/30381407/}, }