% Bibliography for hypothesis h-ba3a948a
% Title: Fractalkine Axis Amplification via CX3CR1 Positive Allosteric Modulators
% Generated: 2026-04-28T13:52:01Z

@article{pmid41542562,
  title = {Microglial Lag3 Drives α-Synuclein-induced Neurotoxic Activated (A1) Astrocytes and Neurodegeneration.},
  author = {["Yang X", "Kumbhar R", "Seo B", "Ha S", "Hinkle J", "Wang N", "Li S", "Niu L", "Liu H", "Stanciu N"]},
  journal = {bioRxiv : the preprint server for biology},
  year = {2026},
  pmid = {41542562},
  doi = {10.64898/2026.01.06.697996},
}

@article{pmid41781900,
  title = {Identification of metabolism and inflammation-related biomarkers and potential drugs for schizophrenia based on comprehensive bioinformatics and machine learning.},
  author = {["Chen Y", "Zhang M", "Qiao L", "Lu F", "Ji S"]},
  journal = {BMC psychiatry},
  year = {2026},
  pmid = {41781900},
  doi = {10.1186/s12888-026-07918-0},
}

@article{pmid41788408,
  title = {Systems-level molecular and immunological evidence identifies Th17/Treg modulation as a key mechanism of CRSJ's neuroprotection in Parkinson's disease.},
  author = {["Li X", "Li X", "Chen S", "Wang L", "Xia J", "Zheng M", "Zhang C", "Chen X", "Cai J"]},
  journal = {Frontiers in aging neuroscience},
  year = {2026},
  pmid = {41788408},
  doi = {10.3389/fnagi.2026.1764634},
}

@article{pmid41799205,
  title = {Multimodal tumor thermal therapy enhances antitumor immunity by expanding tumor-reactive CX3CR1⁺GPR56⁺ T cells in hepatocellular carcinoma.},
  author = {["Wang S", "Wang Y", "Zhang Y", "Zhang Z", "Huang H", "Xu L", "Hao Y", "Lou Y", "Wang K", "Li W"]},
  journal = {Theranostics},
  year = {2026},
  pmid = {41799205},
  doi = {10.7150/thno.127962},
}

@article{pmid41805218,
  title = {Helper T cells and chemokines in elderly asthma - Mechanisms of airway inflammation and remodeling: A review.},
  author = {["Wu Y"]},
  journal = {Biomolecules & biomedicine},
  year = {2026},
  pmid = {41805218},
  doi = {10.17305/bb.2026.13875},
}

@article{pmid41827778,
  title = {Distinct NK Cell Signatures Define Prognosis in HPV-Positive Versus HPV-Negative Head and Neck Cancer.},
  author = {["Li R", "Tong F", "Liu H", "Liu Z", "Li W", "Zhang Y", "Peng Y", "Pan S", "Wei L", "Li N"]},
  journal = {Cancers},
  year = {2026},
  pmid = {41827778},
  doi = {10.3390/cancers18050845},
}

@article{pmid41831796,
  title = {SYK-dependent lipid handling in monocyte-derived macrophages governs functional recovery after spinal cord injury.},
  author = {["Zhao Y", "Hu H", "Wang J", "Hu Y", "Yang L", "Wu Z", "Zhao S", "Wang X", "Mu Y", "Zheng M"]},
  journal = {Brain research bulletin},
  year = {2026},
  pmid = {41831796},
  doi = {10.1016/j.brainresbull.2026.111823},
}

@article{pmid41863015,
  title = {CX3CL1/CX3CR1 axis dysregulation contributes to epileptogenic mechanisms in focal cortical dysplasia.},
  author = {Lei Lei; Shengyu Yang; Yinchao Li; Jiahao Tian; Yubao Fang; Tiancai Huang; Shuda Chen; Liemin Zhou},
  journal = {Acta neuropathologica communications},
  year = {2026},
  pmid = {41863015},
  doi = {10.1186/s40478-026-02274-2},
}

@article{pmid41878553,
  title = {Two-Sample Bidirectional Mendelian Randomization Analysis of the Causal Relationship Between Immune Cell Phenotypes and Systemic Lupus Erythematosus.},
  author = {["Niu W", "Li J", "Jia H", "Wang L", "Xu M", "Liu X"]},
  journal = {Clinical, cosmetic and investigational dermatology},
  year = {2026},
  pmid = {41878553},
  doi = {10.2147/CCID.S566075},
}

@article{pmid41897331,
  title = {Chemokine Networks in Blood-Brain Barrier Regulation: Bidirectional Mechanisms, Clinical Translation, and Precision Therapeutic Prospects.},
  author = {["Wu Q", "Miao Z", "Lei W", "Wu X", "Zhao J", "Sun J"]},
  journal = {Biomolecules},
  year = {2026},
  pmid = {41897331},
  doi = {10.3390/biom16030395},
}

@article{pmid41903685,
  title = {Conserved ductular reaction mechanisms in biliary atresia and PSC derived from single-cell and spatial transcriptomics.},
  author = {Schofield A, Kamath BM, MacParland SA, Trauner M, Trivedi P, Mann JP},
  journal = {Cellular and molecular gastroenterology and hepatology},
  year = {2026},
  pmid = {41903685},
  doi = {10.1016/j.jcmgh.2026.101778},
  url = {https://pubmed.ncbi.nlm.nih.gov/41903685/},
}

@article{pmid41904008,
  title = {G-protein coupled receptor chemokine CX3CR1 influences extracellular Tau internalization in Alzheimer's disease.},
  author = {Chinnathambi S, Rangappa N, Chandrashekar M},
  journal = {Advances in protein chemistry and structural biology},
  year = {2026},
  pmid = {41904008},
  doi = {10.1016/bs.apcsb.2025.10.023},
  url = {https://pubmed.ncbi.nlm.nih.gov/41904008/},
}

@article{pmid41916959,
  title = {Identification of suicide brain transcriptomic signatures using meta-analysis of multiple cohorts.},
  author = {Sokolov AV, Lafta MS, Jokinen J, Schiöth HB},
  journal = {Translational psychiatry},
  year = {2026},
  pmid = {41916959},
  doi = {10.1038/s41398-026-03978-8},
  url = {https://pubmed.ncbi.nlm.nih.gov/41916959/},
}

@article{pmid41923645,
  title = {Microglia-glioblastoma crosstalk mediates glioblastoma invasion at the far infiltration zone.},
  author = {Nebeling FC, Fuhrmann F, Mittag M, Musacchio F, Antony H, Gockel N, Friker LL, Leonardelli S, Filser S, A D, Stork M, Bano D, Pietsch T, Giordano FA, Zhou Q, Parrinello S, Hölzel M, Herrlinger U, Salomoni P, Fuhrmann M},
  journal = {Immunity},
  year = {2026},
  pmid = {41923645},
  doi = {10.1016/j.immuni.2026.03.010},
  url = {https://pubmed.ncbi.nlm.nih.gov/41923645/},
}

@article{pmid41924777,
  title = {Constitutive expression of CX3CR1-BAC-Cre introduces minimal off-target effects in microglia.},
  author = {Mroue-Ruiz FH, Desai B, Garvin MM, Shehu JH, Kamau F, Kar U, Bolton JL},
  journal = {Biochemical and biophysical research communications},
  year = {2026},
  pmid = {41924777},
  doi = {10.1016/j.bbrc.2026.153657},
  url = {https://pubmed.ncbi.nlm.nih.gov/41924777/},
}

@article{pmid41930567,
  title = {[Corrigendum] Influence of aspirin on the CX3CL1/CX3CR1 signaling pathway in acute pulmonary embolism.},
  author = {Zhang Z, Yang W, Ying R, Shi Y, Jiang H et al.},
  journal = {Int J Mol Med},
  year = {2026},
  pmid = {41930567},
  doi = {pii: 148. doi: 10.3892/ijmm.2026.5819},
  url = {https://pubmed.ncbi.nlm.nih.gov/41930567/},
}

@article{pmid41932952,
  title = {CX3CR1-T280M polymorphism and end-stage renal disease development in chronic kidney disease.},
  author = {Matteo Gatti; Ivano Baragetti; Andrea Baragetti; Laura Buzzi; Andrea Lupi; Angelo Fassio; Elena Olmastroni; Alberico L Catapano; Paolo Fabbrini},
  journal = {Scientific reports},
  year = {2026},
  pmid = {41932952},
  doi = {10.1038/s41598-026-40013-8},
  url = {https://pubmed.ncbi.nlm.nih.gov/41932952/},
}

@article{pmid39453382,
  title = {Neuronal cathepsin S increases neuroinflammation and causes cognitive decline via CX3CL1-CX3CR1 axis and JAK2-STAT3 pathway in aging and Alzheimer's disease.},
  author = {Liu PP, Liu XH, Ren MJ, Liu XT, Shi XQ, Li ML, Li SA, Yang Y, Wang DD, Wu Y, Yin FX, Guo YH, Yang RZ, Cheng M, Xin YJ, Kang JS, Huang B, Ren KD},
  journal = {Aging cell},
  year = {2025},
  pmid = {39453382},
  doi = {10.1111/acel.14393},
  url = {https://pubmed.ncbi.nlm.nih.gov/39453382/},
}

@article{pmid41424797,
  title = {CX3CR1: a potential microglia-specific PET imaging target in Alzheimer's and Parkinson's diseases.},
  author = {Yang H, Wang Y, Xu Y, Wang C},
  journal = {Frontiers in pharmacology},
  year = {2025},
  pmid = {41424797},
  doi = {10.3389/fphar.2025.1678159},
  url = {https://pubmed.ncbi.nlm.nih.gov/41424797/},
}

@article{pmid41465422,
  title = {Glial Cells in the Early Stages of Neurodegeneration: Pathogenesis and Therapeutic Targets.},
  author = {Ahremenko E, Andreev A, Apushkin D, Korkotian E},
  journal = {International journal of molecular sciences},
  year = {2025},
  pmid = {41465422},
  doi = {10.3390/ijms262411995},
  url = {https://pubmed.ncbi.nlm.nih.gov/41465422/},
}

@article{pmid38731899,
  title = {CX3CL1 (Fractalkine)-CX3CR1 Axis in Inflammation-Induced Angiogenesis and Tumorigenesis.},
  author = {Szukiewicz D},
  journal = {International journal of molecular sciences},
  year = {2024},
  pmid = {38731899},
  doi = {10.3390/ijms25094679},
  url = {https://pubmed.ncbi.nlm.nih.gov/38731899/},
}

@article{pmid39554070,
  title = {Constitutive expression of CX3CR1-BAC-Cre introduces minimal off-target effects in microglia.},
  author = {["Mroue-Ruiz F", "Desai B", "Garvin M", "Shehu J", "Kamau F", "Kar U", "Bolton J"]},
  journal = {bioRxiv : the preprint server for biology},
  year = {2024},
  pmid = {39554070},
  doi = {10.1101/2024.11.01.621625},
}

@article{pmid37465997,
  title = {Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH.},
  author = {Chen X, He X, Xu F, Xu N, Sharifi NH, Zhang P, Flores JJ, Wu L, He Q, Kanamaru H},
  journal = {Stroke},
  year = {2023},
  pmid = {37465997},
  doi = {10.1161/STROKEAHA.123.043005},
  url = {https://pubmed.ncbi.nlm.nih.gov/37465997},
}

@article{pmid34492237,
  title = {CX3CL1/CX3CR1 signaling targets for the treatment of neurodegenerative diseases.},
  author = {Subbarayan MS, Joly-Amado A, Bickford PC, Nash KR},
  journal = {Pharmacol Ther},
  year = {2022},
  pmid = {34492237},
  doi = {10.1016/j.pharmthera.2021.107989},
  url = {https://pubmed.ncbi.nlm.nih.gov/34492237},
}

@article{pmid35642214,
  title = {Microglia-Mediated Neuroinflammation: A Potential Target for the Treatment of Cardiovascular Diseases.},
  author = {Wang M, Pan W, Xu Y, Zhang J, Wan J, Jiang H},
  journal = {J Inflamm Res},
  year = {2022},
  pmid = {35642214},
  doi = {10.2147/JIR.S350109},
  url = {https://pubmed.ncbi.nlm.nih.gov/35642214},
}

@article{pmid33248023,
  title = {Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia.},
  author = {Wang J, Xu Y, Chen Z, Liang J, Lin Z, Liang H, Xu Y, Wu Q, Guo X, Nie J, Lu B, Huang B, Xian H, Wang X, Wu Q, Zeng J, Chai C, Zhang M, Lin Y, Zhang L, Zhao S, Tong Y, Zeng L, Gu X, Chen ZG, Yi S, Zhang T, Delfouneso D, Zhang Y, Nutt SL},
  journal = {Cell},
  year = {2020},
  pmid = {33248023},
  doi = {10.1016/j.cell.2020.10.048},
  url = {https://pubmed.ncbi.nlm.nih.gov/33248023/},
}

@article{pmid30021162,
  title = {HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants.},
  author = {["Nguyen A", "Ho L", "Workenhe S", "Chen L", "Samson J", "Walsh S", "Pol J", "Bramson J", "Wan Y"]},
  journal = {Cell reports},
  year = {2018},
  pmid = {30021162},
  doi = {10.1016/j.celrep.2018.06.040},
}

@article{pmid30258234,
  title = {Microglia in neurodegeneration.},
  author = {Hickman S, Izzy S, Sen P, Morsett L, El Khoury J},
  journal = {Nat Neurosci},
  year = {2018},
  pmid = {30258234},
  doi = {10.1038/s41593-018-0242-x},
  url = {https://pubmed.ncbi.nlm.nih.gov/30258234},
}

@article{pmid30258234,
  title = {Microglia in neurodegeneration.},
  author = {Hickman S, Izzy S, Sen P, Morsett L, El Khoury J},
  journal = {Nat Neurosci},
  year = {2018},
  pmid = {30258234},
  doi = {doi: 10.1038/s41593-018-0242-x},
  url = {https://pubmed.ncbi.nlm.nih.gov/30258234/},
}

@article{pmid28133889,
  title = {Ni Foam-Ni},
  author = {["Wang X", "Hu J", "Su Y", "Hao J", "Liu F", "Han S", "An J", "Lian J"]},
  journal = {Chemistry (Weinheim an der Bergstrasse, Germany)},
  year = {2017},
  pmid = {28133889},
  doi = {10.1002/chem.201605212},
}

@article{pmid27540165,
  title = {How neuroinflammation contributes to neurodegeneration.},
  author = {Ransohoff RM},
  journal = {Science},
  year = {2016},
  pmid = {27540165},
  doi = {10.1126/science.aag2590},
  url = {https://pubmed.ncbi.nlm.nih.gov/27540165},
}

@article{pmid27540165,
  title = {How neuroinflammation contributes to neurodegeneration.},
  author = {Ransohoff RM},
  journal = {Science},
  year = {2016},
  pmid = {27540165},
  doi = {doi: 10.1126/science.aag2590},
  url = {https://pubmed.ncbi.nlm.nih.gov/27540165/},
}

@article{pmid25157208,
  title = {Specific profile of tau isoforms in argyrophylic grain disease.},
  author = {["R\u00e1bano A", "Cuadros R", "Calero M", "Hern\u00e1ndez F", "Avila J"]},
  journal = {Journal of experimental neuroscience},
  year = {2013},
  pmid = {25157208},
  doi = {10.4137/JEN.S12202},
}

@article{pmid21778362,
  title = {Synaptic pruning by microglia is necessary for normal brain development.},
  author = {["Paolicelli R", "Bolasco G", "Pagani F", "Maggi L", "Scianni M", "Panzanelli P", "Giustetto M", "Ferreira T", "Guiducci E", "Dumas L"]},
  journal = {Science (New York, N.Y.)},
  year = {2011},
  pmid = {21778362},
  doi = {10.1126/science.1202529},
}

@article{pmid27156590,
  title = {The Role of Functional Imaging in Radiotherapy Planning and Management for Gynecologic Malignancies.},
  author = {["Ma D", "Guo S", "Shah S", "Srinivas S", "Macklis R"]},
  journal = {PET clinics},
  year = {2011},
  pmid = {27156590},
  doi = {10.1016/j.cpet.2011.02.006},
}

@article{pmid20980594,
  title = {Visual representations by cortical somatostatin inhibitory neurons--selective but with weak and delayed responses.},
  author = {["Ma W", "Liu B", "Li Y", "Huang Z", "Zhang L", "Tao H"]},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year = {2010},
  pmid = {20980594},
  doi = {10.1523/JNEUROSCI.3248-10.2010},
}