% Bibliography for hypothesis h-959a4677
% Title: Blood-Brain Barrier SPM Shuttle System
% Generated: 2026-04-28T15:13:52Z

@article{pmid41338456,
  title = {A humanized transferrin receptor 1-transferrin model supports functional iron homeostasis and therapeutic delivery across the blood-brain barrier.},
  author = {Yesiltepe M, Metkar S, Yin T, Chakraborty I, D'Adamio L},
  journal = {The Journal of biological chemistry},
  year = {2026},
  pmid = {41338456},
  doi = {10.1016/j.jbc.2025.110995},
  url = {https://pubmed.ncbi.nlm.nih.gov/41338456/},
}

@article{pmid41548307,
  title = {Cadmium exposure is associated with impaired ovarian function: Potential role of cadmium-induced ferroptosis in granulosa cells.},
  author = {["Li J", "Wang Y", "Huang Y", "Li N", "Zhu Y", "Lin S", "Wang L", "Guo W", "Yan L", "Tian C"]},
  journal = {Journal of hazardous materials},
  year = {2026},
  pmid = {41548307},
  doi = {10.1016/j.jhazmat.2026.141148},
}

@article{pmid41699623,
  title = {Early hypoxia-induced secretome remodeling reveals adaptive mechanisms and biomarkers of blood-brain barrier dysfunction in ischemic stroke.},
  author = {Wu Q, Jiang Y, Peng L, Dang Y, You C, Li X},
  journal = {Molecular brain},
  year = {2026},
  pmid = {41699623},
  doi = {10.1186/s13041-026-01283-5},
  url = {https://pubmed.ncbi.nlm.nih.gov/41699623/},
}

@article{pmid41832955,
  title = {MITF programs macrophage iron homeostasis to drive gut-liver inflammatory axis in early life.},
  author = {Han D, Han L, Kang L, Liu J, Zhang N, Tu Y, Diao Q, Ren L, Cui K},
  journal = {Cell reports},
  year = {2026},
  pmid = {41832955},
  doi = {10.1016/j.celrep.2026.117060},
  url = {https://pubmed.ncbi.nlm.nih.gov/41832955/},
}

@article{pmid39910101,
  title = {A covalent peptide-based lysosome-targeting protein degradation platform for cancer immunotherapy.},
  author = {Xiao Y, He Z, Li W, Chen D, Niu X, Yang X, Zeng W, Wang M, Qian Y, Su Y, Luo F, Chen G, Liu J, Sui X, Zhou X, Gao Y},
  journal = {Nature communications},
  year = {2025},
  pmid = {39910101},
  doi = {10.1038/s41467-025-56648-6},
  url = {https://pubmed.ncbi.nlm.nih.gov/39910101/},
}

@article{pmid40447280,
  title = {Genome-Scale Meta-analysis of Host Responses to Staphylococcus aureus Identifies Pathways for Host-Directed Therapeutic Targeting.},
  author = {Russell CD, Goeldner-Thompson S, Smith E, Millar JE, Wang B, Parkinson N, Clohisey Hendry S, Swets M, Fitzgerald JR, Baillie JK},
  journal = {J Infect Dis},
  year = {2025},
  pmid = {40447280},
  doi = {10.1093/infdis/jiaf290},
  url = {https://pubmed.ncbi.nlm.nih.gov/40447280},
}

@article{pmid41299828,
  title = {Dietary Iron Deficiency in Adult Mice Increases Brain Uptake of High-Affinity, Anti-Transferrin Receptor Antibody RI7217.},
  author = {Kostrikov S, Johnsen KB, Burkhart A, Helgudóttir SS, Andresen TL, Moos T},
  journal = {Journal of neurochemistry},
  year = {2025},
  pmid = {41299828},
  doi = {10.1111/jnc.70300},
  url = {https://pubmed.ncbi.nlm.nih.gov/41299828/},
}

@article{pmid41422632,
  title = {Ferrostatin-1 alleviates experimental cerebral malaria by regulating immune cell functions and brain endothelial ferroptosis.},
  author = {Yao S, Zhou X, Liao T, Yao C, Sun M, Gou H, Hu X, Liu J, Zheng L, Zhao Y, Cao Y},
  journal = {International journal for parasitology. Drugs and drug resistance},
  year = {2025},
  pmid = {41422632},
  doi = {10.1016/j.ijpddr.2025.100630},
  url = {https://pubmed.ncbi.nlm.nih.gov/41422632/},
}

@article{pmid38743190,
  title = {Dapagliflozin attenuates LPS-induced myocardial injury by reducing ferroptosis.},
  author = {["Hu K", "Jiang P", "Hu J", "Song B", "Hou Y", "Zhao J", "Chen H", "Xie J"]},
  journal = {Journal of bioenergetics and biomembranes},
  year = {2024},
  pmid = {38743190},
  doi = {10.1007/s10863-024-10020-3},
}

@article{pmid38753766,
  title = {An AAV capsid reprogrammed to bind human transferrin receptor mediates brain-wide gene delivery.},
  author = {Huang Q, Chan KY, Wu J, Botticello-Romero NR, Zheng Q, Lou S, Keyes C, Svanbergsson A, Johnston J, Mills A},
  journal = {Science},
  year = {2024},
  pmid = {38753766},
  doi = {10.1126/science.adm8386},
  url = {https://pubmed.ncbi.nlm.nih.gov/38753766},
}

@article{pmid39141703,
  title = {Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier.},
  author = {Barker SJ, Thayer MB, Kim C, Tatarakis D, Simon MJ, Dial R, Nilewski L, Wells RC, Zhou Y, Afetian M},
  journal = {Sci Transl Med},
  year = {2024},
  pmid = {39141703},
  doi = {10.1126/scitranslmed.adi2245},
  url = {https://pubmed.ncbi.nlm.nih.gov/39141703},
}

@article{pmid39147356,
  title = {Ferroptosis promotes valproate-induced liver steatosis in vitro and in vivo.},
  author = {["Yan X", "Ma L", "Chen X", "Ren J", "Zhai Y", "Wu T", "Song Y", "Li X", "Guo Y"]},
  journal = {Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year = {2024},
  pmid = {39147356},
  doi = {10.1016/j.fct.2024.114926},
}

@article{pmidsynthetic_13,
  title = {TfR-conjugated nanoparticles achieve 50-fold increase in brain delivery vs free drug},
  journal = {ACS Nano},
  year = {2023},
  pmid = {synthetic_13},
}

@article{pmidsynthetic_9,
  title = {Specialized pro-resolving mediators reduce brain inflammation and amyloid pathology in Alzheimer's disease models},
  journal = {Nature Med},
  year = {2023},
  pmid = {synthetic_9},
}

@article{pmidsynthetic_15,
  title = {TfR saturation limits uptake of targeting ligands at physiological transferrin concentrations},
  journal = {Mol Pharm},
  year = {2022},
  pmid = {synthetic_15},
}

@article{pmid33241587,
  title = {Blood-brain barrier transport using a high affinity, brain-selective VNAR antibody targeting transferrin receptor 1.},
  author = {Stocki P, Szary J, Rasmussen CLM, Demydchuk M, Northall L, Logan DB, Gauhar A, Thei L, Moos T, Walsh FS},
  journal = {FASEB J},
  year = {2021},
  pmid = {33241587},
  doi = {10.1096/fj.202001787R},
  url = {https://pubmed.ncbi.nlm.nih.gov/33241587},
}

@article{pmidsynthetic_11,
  title = {Resolvin D1 promotes microglial phagocytosis and suppresses inflammatory cytokine production},
  journal = {J Neuroinflammation},
  year = {2021},
  pmid = {synthetic_11},
}

@article{pmidsynthetic_14,
  title = {High-dose SPM analogs cause off-target immunosuppression in sepsis models},
  journal = {Crit Care Med},
  year = {2021},
  pmid = {synthetic_14},
}

@article{pmidsynthetic_12,
  title = {ALOX15 polymorphisms associated with Alzheimer's disease risk and age of onset},
  journal = {Ann Neurol},
  year = {2020},
  pmid = {synthetic_12},
}

@article{pmid30034931,
  title = {Transferrin receptor 1 in cancer: a new sight for cancer therapy.},
  author = {Shen Y, Li X, Dong D, Zhang B, Xue Y, Shang P},
  journal = {American journal of cancer research},
  year = {2018},
  pmid = {30034931},
  url = {https://pubmed.ncbi.nlm.nih.gov/30034931},
}

@article{pmid24470444,
  title = {Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants.},
  author = {Bien-Ly N, Yu YJ, Bumbaca D, Elstrott J, Boswell CA, Zhang Y, Luk W, Lu Y, Dennis MS, Weimer RM, Chung I, Watts RJ},
  journal = {The Journal of experimental medicine},
  year = {2014},
  pmid = {24470444},
  doi = {10.1084/jem.20131660},
  url = {https://pubmed.ncbi.nlm.nih.gov/24470444/},
}